Preliminary Findings

RESULTS

Read below for coverage of our most exciting and engaging outreach event - the Tick Immunity Symposium - where we share and discuss our work with the broader scientific community, thanks to P01 funding from the NIH.

Preliminary findings related to this project are also highlighted below.

Up-to-date results from our studies can be found in the Publications tab, which lists all relevant peer-reviewed literature from this program. For information about the technologies and methodologies that have been created or optimized through our project, please refer to the Technical Resources tab.

Message in a Vesicle – Trans-kingdom Intercommunication

Mar 18, 2019

Preliminary Findings

Message in a Vesicle – Trans-kingdom Intercommunication

Joao H. F. Pedra of the University of Maryland School of Medicine and his team published a new review paper that briefly discusses...

Role of Mannose Binding Lectin in the Immune Response against Borrelia

Feb 5, 2019

Preliminary Findings

Role of Mannose Binding Lectin in the Immune Response against Borrelia

Erol Fikrig and team at the Yale University School of Medicine published a new paper examining the role of Mannose Binding Lectin (MBL)...

Mutational Analysis of Gene function in the Anaplasmataceae

Feb 1, 2019

Preliminary Findings

Mutational Analysis of Gene function in the Anaplasmataceae

Ulrike Munderloh and team at the University of Minnesota published a new paper on mutational analysis of gene function. Mutational...

Borrelia Protein Interactions Critical for Persistence in Mammals

Feb 1, 2019

Preliminary Findings

Borrelia Protein Interactions Critical for Persistence in Mammals

Utpal Pal and team at the University of Maryland, College Park published a review on the interactions between Borrelia burgdorferi...

Activation of the Immune Deficiency Pathway in Black-legged Ticks

Jan 2, 2019

Preliminary Findings

Activation of the Immune Deficiency Pathway in Black-legged Ticks

Researchers identify the molecule p47 as a binding partner that induces a signaling cascade to limit microbial infection Researchers at...

Characterization of Tick OATPs on Bacterial and Viral Infections

Nov 14, 2018

Preliminary Findings

Characterization of Tick OATPs on Bacterial and Viral Infections

Utpal Pal and his team at the University of Maryland, College Park, published a new paper characterizing the roles of Ixodes scapularis ...

Vector Immunity and Evolutionary Ecology: The Harmonious Dissonance

Nov 1, 2018

Preliminary Findings

Vector Immunity and Evolutionary Ecology: The Harmonious Dissonance

How evolution has shaped vector immunity, calling for immunologists and evolutionary ecologists to work together to tackle some of these...

Identification of Lyme Borreliae Proteins Promoting Survival in Ixodes Nymphs

Jul 1, 2018

Preliminary Findings

Identification of Lyme Borreliae Proteins Promoting Survival in Ixodes Nymphs

Utpal Pal and team at the University of Maryland, College Park, published a new paper identifying proteins that affect survival of...

Visualization of Microbiota in Tick Guts by Whole-mount In Situ Hybridization

Jun 1, 2018

Preliminary Findings

Visualization of Microbiota in Tick Guts by Whole-mount In Situ Hybridization

Erol Fikrig and team from the Yale University School of Medicine have published a method to visualize the microbiota in tick guts using...

Host-Specific Expression of Tick Salivary Genes

Jun 1, 2018

Preliminary Findings

Host-Specific Expression of Tick Salivary Genes

Findings provide new insight into vector-host interactions and offer a functional paradigm to better understand the phenomenon of...

Ixodes Immune Responses Against Lyme Disease Pathogens

May 29, 2018

Preliminary Findings

Ixodes Immune Responses Against Lyme Disease Pathogens

Utpal Pal and team at the University of Maryland, College Park, published a new review of recent studies in immune response against Lyme...

Borrelia Surface Protein Processed into Peptides for Microbial Persistence

May 10, 2018

Preliminary Findings

Borrelia Surface Protein Processed into Peptides for Microbial Persistence

Utpal Pal and team at the University of Maryland, College Park, published a new paper highlighting a newly discovered mechanism for...

Protein Used to Outsmart the Human Immune System

Apr 2, 2018

Preliminary Findings

Protein Used to Outsmart the Human Immune System

Findings have major implications for tick-borne diseases like Lyme disease A UMD researcher has uncovered a mechanism by which the...

Methods in Microbiology: Artificial Infection of Ticks with Borrelia

Oct 15, 2017

Preliminary Findings

Methods in Microbiology: Artificial Infection of Ticks with Borrelia

Utpal Pal of the University of Maryland, College Park, edited a book in the Methods in Microbiology series on Borrelia burgdorferi...